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==The Left Ventricular==
==The Left Ventricle==


There is still much uncertainty about the pathophysiology of diastolic heart failure, which still lacks an effective treatment, with a high mortality related to diastolic heart failure over the last decades. Diastolic heart failure is characterized by an increased LV diastolic stiffness. Echocardiographic there are some important measurements are indispensable to good to estimate. Stiffness in the standard ultrasound examination.
There is still much uncertainty about the pathophysiology of diastolic heart failure, effective treatment has not surfaced yet while it has a similar high mortality and morbidity rate when compared to systolic heart failure. One of the characteristics of diastolic heart failure is an increased LV diastolic stiffness. There are several important measurements echocardiographic measurement to estimate cardiac diastolic performance.


==Left ventricular diastolic function==
==Left ventricular diastolic function==
{| class="wikitable" cellpadding="0" cellspacing="0" border="0" width="800px"
|-
!colspan="6"|
===Normal Values ​​diastolic parameters===
===Normal Values ​​diastolic parameters===
|-
!rowspan="2" valign="middle"|Measurement
!colspan="4"|Age group (y)
|-
!16-20
!21-40
!41-60
!>60
|-
!IVRT (ms)
|50 ± 9 (32-68)  
|67 ± 8 (51-83)  
|74 ± 7 (60-88)  
|87 ± 7 (73-101)
|-
!E/A ratio  
|1.88 ± 0.45 (0.98-2.78)  
|1.53 ± 0.40 (0.73-2.33)  
|1.28 ± 0.25 (0.78-1.78)  
|0.96 ± 0.18 (0.6-1.32)
|-
!DT (ms)  
|142 ± 19 (104-180)  
|166 ± 14 (138-194)  
|181 ± 19 (143-219)  
|200 ± 29 (142-258)
|-
!A duration (ms)  
|113 ± 17 (79-147)  
|127 ± 13 (101-153)  
|133 ± 13 (107-159)  
|138 ± 19 (100-176)
|-
!PV S/D ratio  
|0.82 ± 0.18 (0.46-1.18)  
|0.98 ± 0.32 (0.34-1.62)  
|1.21 ± 0.2 (0.81-1.61)  
|1.39 ± 0.47 (0.45-2.33)
|-
!PV Ar (cm/s)  
|16 ± 10 (1-36)  
|21 ± 8 (5-37)  
|23 ± 3 (17-29)  
|25 ± 9 (11-39)
|-
!PV Ar duration (ms)  
|66 ± 39 (1-144)  
|96 ± 33 (30-162)  
|112 ± 15 (82-142)  
|113 ± 30 (53-173)
|-
!Septal e´ (cm/s)
|14.9 ± 2.4 (10.1-19.7)  
|15.5 ± 2.7 (10.1-20.9)  
|12.2 ± 2.3 (7.6-16.8)  
|10.4 ± 2.1 (6.2-14.6)
|-
!Septal e´/a´ ratio
|2.4*  
|1.6 ± 0.5 (0.6-2.6)  
|1.1 ± 0.3 (0.5-1.7)  
|0.85 ± 0.2 (0.45-1.25)
|-
!Lateral e´ (cm/s)  
|20.6 ± 3.8 (13-28.2)  
|19.8 ± 2.9 (14-25.6)  
|16.1 ± 2.3 (11.5-20.7)  
|12.9 ± 3.5 (5.9-19.9)
|-
!Lateral e´/a´ ratio
|3.1*  
|1.9 ± 0.6 (0.7-3.1)  
|1.5 ± 0.5 (0.5-2.5)  
|0.9 ± 0.4 (0.1-1.7)
|-
|colspan="6"|
*Data are expressed as mean ± SD (95% confidence interval). Note that for e´ velocity in subjects aged 16 to 20 years, values overlap with those for subjects aged 21 to 40 years. This is because e´ increases progressively with age in children and adolescents. Therefore, the e´ velocity is higher in a normal 20-year-old than in a normal 16-year-old, which results in a somewhat lower average e´ value when subjects aged 16 to 20 years are considered.<cite>1</cite>
*<nowiki>*</nowiki>Standard deviations are not included because these data were computed, not directly provided in the original articles from which they were derived.
|}


{| class="wikitable" cellpadding="0" cellspacing="0" border="0" width="800px"
|-
!
===Schematic diastolic filling patterns===
===Schematic diastolic filling patterns===
|-
|'''A patient with dyspnea, preserved systolic LV function, dilated left atrium and elevated pulmonary artery systolic pressure, without any significant mitral valve disease that could explain these findings, is the patient that requires an intensified search for diastolic LV dysfunction.'''
|-
|align="center" bgcolor="FFFFFF"|[[Image:Diastole.svg]]
|-
|'''I:''' impaired relaxation, '''II:''' moderate diastolic dysfunction (pseudonormal), '''III:''' restrictive left ventricular filling (impaired LV compliance), ECG: electrocardiogram, MI: mitral inflow, MA: mitral annular velocities, PVF: pulmonary venous flow, Vp: velocity of flow progression, LA: left atrium, PASP: pulmonary artery systolic pressure.<cite>2</cite>


[[Image:Diastole.jpg]]
Click [http://www.ecocardiografia.info/didat_diast_en_II.htm '''here'''] for animation on diastolic dysfunction
|}


===Diastolic function flowchart===
{| class="wikitable" cellpadding="0" cellspacing="0" border="0" width="800px"
|-
!


[[Image:500px-Diastolicfunction svg.png]]
===Diastolic function flowchart <cite>1</cite>===
|-
|align="center" bgcolor="FFFFFF"|[[Image:500px-Diastolicfunction svg.png]]
|}


==References==
==References==
<biblio>
#1 pmid=19270053
</biblio>
==External links==
* [https://www.techmed.sk/en/echo/diastolic-function/ Diastolic Function - all measurements (TECHmED)]
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